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In its 48-week Phase 2 trial, Retatrutide achieved a mean weight reduction of up to 24.2% at the highest dose

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doi: 10.1007/s11596-020-2210-4

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But initial results were disappointing

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15 Of important interest was their effects in weight loss even in non-diabetic patients

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The observed Exe4 secretion in Donor-transfected cells is likely due to leakage expression from the promoter-less donor, as reported previously (Fig

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